CL1_0359 protein (Thermococcus cleftensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CL1_0359

RNA binding protein containing KH domain; COG0195. (170 aa)

Predicted Functional Partners:

CL1_0440

0.882

rpoD

0.855

rps2

0.831

rps5

0.831

rps7

0.822

rpl11

0.819

spt5

0.814

rps12

0.813

rps9

0.810

rpl5

0.807

Your Current Organism:

Thermococcus cleftensis

NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CL1_0359	CL1_0440	CL1_0359	CL1_0440	RNA binding protein containing KH domain; COG0195.	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.882
CL1_0359	rpl11	CL1_0359	CL1_0400	RNA binding protein containing KH domain; COG0195.	50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.	0.819
CL1_0359	rpl5	CL1_0359	CL1_0614	RNA binding protein containing KH domain; COG0195.	50S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.	0.807
CL1_0359	rpoD	CL1_0359	CL1_0593	RNA binding protein containing KH domain; COG0195.	DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.	0.855
CL1_0359	rps12	CL1_0359	CL1_0445	RNA binding protein containing KH domain; COG0195.	30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	0.813
CL1_0359	rps2	CL1_0359	CL1_0586	RNA binding protein containing KH domain; COG0195.	30S ribosomal protein S2; COG0052; Belongs to the universal ribosomal protein uS2 family.	0.831
CL1_0359	rps5	CL1_0359	CL1_0607	RNA binding protein containing KH domain; COG0195.	30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.	0.831
CL1_0359	rps7	CL1_0359	CL1_0446	RNA binding protein containing KH domain; COG0195.	30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.	0.822
CL1_0359	rps9	CL1_0359	CL1_0590	RNA binding protein containing KH domain; COG0195.	30S ribosomal protein S9; COG0103; Belongs to the universal ribosomal protein uS9 family.	0.810
CL1_0359	spt5	CL1_0359	CL1_0399	RNA binding protein containing KH domain; COG0195.	Transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.	0.814
CL1_0440	CL1_0359	CL1_0440	CL1_0359	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA binding protein containing KH domain; COG0195.	0.882
CL1_0440	rpl11	CL1_0440	CL1_0400	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.	0.992
CL1_0440	rpl5	CL1_0440	CL1_0614	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	50S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.	0.989
CL1_0440	rpoD	CL1_0440	CL1_0593	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.	0.999
CL1_0440	rps12	CL1_0440	CL1_0445	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	0.994
CL1_0440	rps2	CL1_0440	CL1_0586	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	30S ribosomal protein S2; COG0052; Belongs to the universal ribosomal protein uS2 family.	0.968
CL1_0440	rps5	CL1_0440	CL1_0607	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.	0.991
CL1_0440	rps7	CL1_0440	CL1_0446	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.	0.996
CL1_0440	rps9	CL1_0440	CL1_0590	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	30S ribosomal protein S9; COG0103; Belongs to the universal ribosomal protein uS9 family.	0.985
CL1_0440	spt5	CL1_0440	CL1_0399	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.	0.971