STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0449Putative sulfur carrier protein ThiS; COG2104. (67 aa)    
Predicted Functional Partners:
CL1_1100
Hypothetical protein; COG0476.
  
 
 0.889
thiC
Putative thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.887
CL1_0035
Putative phosphomethylpyrimidine kinase; COG1992.
  
    0.867
CL1_1564
Hypothetical protein containing JAB1/MPN domain; COG1310.
  
 
 0.695
CL1_0154
Metalloprotease containing JAB1/MPN domain; COG1310.
  
 
 0.660
CL1_0970
Hypothetical protein; COG0037.
  
 
 0.553
CL1_0999
Putative ATPase 2; COG0037.
  
 
 0.553
CL1_0104
Putative ATPase 1; COG0037.
  
 
 0.533
CL1_0924
Hypothetical protein; COG0037.
  
 
 0.533
CL1_0450
Hypothetical protein; COG1570.
       0.464
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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