Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpl44e50S ribosomal protein L44e; Binds to the 23S rRNA. (94 aa)    
Predicted Functional Partners:
rpl30e
50S ribosomal protein L30e; COG1911; Belongs to the eukaryotic ribosomal protein eL30 family.
   
 0.999
rps27e
30S ribosomal protein S27e; COG2051.
  
 
 0.999
rpl40e
50S ribosomal protein L40e; COG1552; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 0.999
rpl18
50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
 0.999
rpl19e
50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
  
 0.999
rpl32e
50S ribosomal protein L32e; COG1717; Belongs to the eukaryotic ribosomal protein eL32 family.
  
 0.999
rpl22
50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
   
 0.999
rpl31e
50S ribosomal protein L31e; COG2097; Belongs to the ribosomal protein L31e family.
   
 0.999
rpl24e
50S ribosomal protein L24e; Binds to the 23S rRNA.
  
 0.999
rps15
30S ribosomal protein S15; COG0184.
  
 
 0.998
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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