Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_0464Cobalt ABC transporter permease 1, CbiQ; COG0619. (219 aa)    
Predicted Functional Partners:
CL1_0462
Cobalt ABC transporter permease, CbiM; COG0310.
 
 
 0.997
CL1_0465
Cobalt ABC transporter ATPase 1; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
 
 0.997
CL1_0463
Cobalt ABC transport protein, CbiN; COG0310.
  
 
 0.991
CL1_1696
Cobalt ABC transporter ATPase 2; COG1122.
 
 
 0.838
CL1_0296
Cobalt transporter ATP-binding protein; COG1122.
 
 
 0.781
CL1_1697
Putative biotin biosynthesis protein BioY; COG1268.
  
 
 0.702
nop10
Putative H/ACA RNA-protein complex component Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
       0.621
CL1_0461
Hypothetical protein; COG2047.
       0.621
eif2a
Translation initiation factor IF-2 subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.
       0.618
CL1_1121
Hypothetical protein; COG4720.
  
 
 0.573
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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