STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_0467Putative phospho-sugar mutase; COG1109. (456 aa)    
Predicted Functional Partners:
CL1_0469
Bifunctional mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; COG0836; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
 0.993
CL1_0109
Putative sugar-phosphate nucleotidyltransferase; COG1208.
 
 0.991
CL1_0414
Putative mannose-1-phosphate guanylyltransferase; COG1208.
 
 
 0.991
CL1_0291
Sugar-phosphate nucleotidyltransferase 1; COG1208.
 
 0.988
glkA
ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor.
    
 0.983
CL1_0840
Sugar-phosphate nucleotidyltransferase 2; COG1208.
 
 0.983
CL1_0471
Glucose-6-phosphate isomerase; COG2140.
    
 0.969
CL1_0412
Alpha-glucan phosphorylase; COG0058.
 
 
 0.937
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
 
 0.933
CL1_1233
Hypothetical protein containing ribokinase-like domain 2; COG0524; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.926
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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