STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0490Hydrogenase expression/formation protein HypE 2; COG0309. (338 aa)    
Predicted Functional Partners:
CL1_0486
Hydrogenase expression/formation protein hypD; COG0409.
 
 
 0.997
CL1_0485
Hydrogenase expression/formation protein HypC; COG0298.
 
 
 0.994
CL1_0487
Hydrogenase maturation protein HypF; COG0068.
 
 
 0.986
CL1_0488
Hypothetical protein; COG1708.
       0.916
CL1_0489
Hypothetical protein; COG1895.
       0.916
hypA
Hydrogenase nickel incorporation protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.775
CL1_0491
Hypothetical protein.
       0.660
CL1_0492
Putative cysteine desulfurase; COG0520.
       0.660
CL1_1151
Coenzyme F420 hydrogenase subunit alpha (frhA); COG3259.
 
   
 0.613
CL1_1131
NADH-ubiquinone oxidoreductase subunit 2; COG3261.
     
 0.431
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.