Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CL1_0499Major facilitator superfamily permease 4; COG0477. (414 aa)    
Predicted Functional Partners:
CL1_0386
Transcription regulator, ArsR family 5; COG1777.
  
     0.555
CL1_1856
Putative transcription regulator, containing DNA-binding HTH domain; COG3413.
 
     0.547
CL1_1591
Hypothetical protein.
  
     0.538
CL1_1211
Hypothetical protein; COG1549.
  
    0.479
CL1_0351
Hypothetical protein; COG1849.
  
     0.475
CL1_0154
Metalloprotease containing JAB1/MPN domain; COG1310.
  
 
 
 0.440
CL1_0497
Hypothetical protein; COG3391.
       0.427
CL1_0498
Hypothetical protein; COG0243.
       0.427
CL1_1160
ABC type transporter permease 1; COG0842.
 
   
 0.418
CL1_1346
Putative transcription regulator, penicillinase repressor family; COG3682.
  
     0.407
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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