STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0500Putative NADH-oxidase 2; COG0446. (441 aa)    
Predicted Functional Partners:
CL1_1148
Formate hydrogen lyase subunit alpha; COG0243.
    
 0.752
CL1_0638
Glutamate synthase beta chain-related oxidoreductase containing 2Fe-2S and 4Fe-4S clusters; COG0493.
   
 
0.724
CL1_0794
Formate dehydrogenase subunit alpha FdhA; COG0243.
    
 0.701
CL1_0501
Putative nonsense-mediated mRNA decay protein, NMD3-family; COG1499.
       0.678
CL1_0502
Hypothetical protein; COG2412.
       0.595
CL1_1369
Hypothetical protein; COG0665.
  
 
 0.523
CL1_1380
Hypothetical protein; COG0665.
  
 
 0.523
rps5
30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
  
 
 0.470
upp
Putative uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
   0.433
rps10
30S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 
 0.402
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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