STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0500Putative NADH-oxidase 2; COG0446. (441 aa)    
Predicted Functional Partners:
CL1_0501
Putative nonsense-mediated mRNA decay protein, NMD3-family; COG1499.
       0.855
CL1_0502
Hypothetical protein; COG2412.
       0.818
CL1_0190
Putative monovalent cation/H+ antiporter 1 subunit E; COG1863.
      
 0.776
CL1_1148
Formate hydrogen lyase subunit alpha; COG0243.
    
 0.748
CL1_0794
Formate dehydrogenase subunit alpha FdhA; COG0243.
    
 0.696
CL1_0638
Glutamate synthase beta chain-related oxidoreductase containing 2Fe-2S and 4Fe-4S clusters; COG0493.
   
 
 0.564
CL1_0385
Glutaredoxin-like protein 2; COG0526.
   
 
 0.458
CL1_0200
NADH dehydrogenase subunit C; COG0852.
   
 
 0.427
CL1_0202
NADH dehydrogenase subunit I; COG1143.
     
 0.414
CL1_0487
Hydrogenase maturation protein HypF; COG0068.
  
  
 0.413
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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