Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_0502Hypothetical protein; COG2412. (99 aa)    
Predicted Functional Partners:
CL1_0501
Putative nonsense-mediated mRNA decay protein, NMD3-family; COG1499.
       0.868
CL1_0500
Putative NADH-oxidase 2; COG0446.
       0.818
CL1_0652
Cell division control protein, MCM family; COG1241.
 
     0.764
CL1_0448
Hypothetical protein; Involved in DNA damage repair.
  
     0.623
CL1_1915
Hypothetical protein containing KH domain; COG1094.
 
     0.623
CL1_1058
Cell division control protein 6; Involved in regulation of DNA replication.
  
     0.614
CL1_0503
Stetterlysin-like protease; COG1404; Belongs to the peptidase S8 family.
       0.612
ribK
Putative transcription regulator, MarR family 1; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.606
CL1_0506
Hypothetical protein; COG1822.
       0.593
dtdA
Hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
  
     0.592
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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