Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CL1_0503Stetterlysin-like protease; COG1404; Belongs to the peptidase S8 family. (1422 aa)    
Predicted Functional Partners:
CL1_0502
Hypothetical protein; COG2412.
       0.612
CL1_0501
Putative nonsense-mediated mRNA decay protein, NMD3-family; COG1499.
       0.497
CL1_0971
Hypothetical protein containing peptidase S8-domain; COG1404.
 
     0.495
CL1_1898
Amino acid transporter; COG0531.
  
 
 0.440
CL1_0504
Hypothetical protein.
       0.425
CL1_0505
Hypothetical protein; COG1822.
       0.425
CL1_0506
Hypothetical protein; COG1822.
       0.424
CL1_0507
Glycosyl transferase family protein 6; COG1807.
       0.417
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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