close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0508Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (784 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
  
 0.941
CL1_0587
Enolase-like protein; COG0148.
 
  
 0.932
CL1_1896
Pyruvate kinase; COG0469; Belongs to the pyruvate kinase family.
   
 0.931
CL1_1805
Pyruvate carboxylase subunit B; COG5016.
   
 
 0.929
CL1_1264
NADP-dependent malic enzyme; COG0281.
    
 0.921
CL1_1249
Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; COG1014.
  
 
 0.920
CL1_1245
Pyruvate ferredoxin oxidoreductase subunit delta; COG1144.
    
 0.919
CL1_0008
2-oxoglutarate ferredoxin oxidoreductase subunit beta 1; COG1013.
    
 0.913
CL1_0011
2-oxoglutarate ferredoxin oxidoreductase subunit beta 2; COG1013.
    
 0.913
CL1_1243
Pyruvate ferredoxin oxidoreductase subunit beta; COG1013.
    
 0.913
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.