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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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CL1_0508Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (784 aa)    
Predicted Functional Partners:
CL1_1896
Pyruvate kinase; COG0469; Belongs to the pyruvate kinase family.
    
 0.979
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
  
 0.964
CL1_1805
Pyruvate carboxylase subunit B; COG5016.
   
 
 0.944
CL1_1245
Pyruvate ferredoxin oxidoreductase subunit delta; COG1144.
    
 0.937
CL1_1264
NADP-dependent malic enzyme; COG0281.
    
 0.937
CL1_0587
Enolase-like protein; COG0148.
 
  
 0.928
CL1_1249
Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; COG1014.
  
 
 0.919
pckG
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
     
 0.912
CL1_0009
2-oxoglutarate ferredoxin oxidoreductase subunit alpha 1; COG0674.
    
 0.910
CL1_0012
2-oxoglutarate ferredoxin oxidoreductase subunit alpha 2; COG0674.
    
 0.910
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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