STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0543Sodium-dependent transporter; COG0733; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (511 aa)    
Predicted Functional Partners:
CL1_0544
Alpha-glucosidase related protein.
       0.581
CL1_1382
Sodium:solute symporter family protein; COG0591; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.568
CL1_1454
Hypothetical protein; COG0428.
 
  
 0.547
CL1_1195
Sodium/hydrogen antiporter, NhaC-type; COG1757.
 
   
 0.522
CL1_1808
Proton/glutamate symporter; COG1301.
 
  
 0.481
CL1_1898
Amino acid transporter; COG0531.
  
 
 0.450
CL1_0862
Ribonucleoside-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
 
   
 0.428
CL1_1027
Hypothetical protein; COG1161.
  
   
 0.419
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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