Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0545Nitrogen regulatory protein P-II (glnB); COG0347; Belongs to the P(II) protein family. (105 aa)    
Predicted Functional Partners:
CL1_0546
Glycogen branching enzyme; COG1543; Belongs to the glycosyl hydrolase 57 family.
  
    0.851
CL1_0909
Glutamine synthetase; COG0174; Belongs to the glutamine synthetase family.
  
 
 0.832
CL1_0547
Hypothetical protein containing fibronectin-binding protein; COG1293.
       0.735
CL1_1601
Asparagine synthase; COG0367.
 
   
 0.548
CL1_0638
Glutamate synthase beta chain-related oxidoreductase containing 2Fe-2S and 4Fe-4S clusters; COG0493.
  
  
 0.520
CL1_0034
Hypothetical protein; COG1028.
   
 
 0.465
CL1_0236
Hypothetical protein; COG0457.
   
 
 0.465
CL1_0297
Hypothetical protein.
   
 
 0.465
CL1_0476
Hypothetical protein; COG0457.
   
 
 0.465
CL1_0819
Hypothetical protein; COG0457.
   
 
 0.465
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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