STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0553Hypothetical protein; COG1325. (151 aa)    
Predicted Functional Partners:
rnp3
Ribonuclease P protein component 3; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
 
     0.761
CL1_1455
Hypothetical protein; COG1931; Belongs to the UPF0201 family.
  
   
 0.712
CL1_0554
Hypothetical protein containing AbrB/MazE/MraZ-like domain; COG2002.
       0.588
CL1_0555
Hypothetical protein.
       0.588
CL1_0501
Putative nonsense-mediated mRNA decay protein, NMD3-family; COG1499.
  
     0.538
rps3ae
30S ribosomal protein S3Ae; COG1890; Belongs to the eukaryotic ribosomal protein eS1 family.
 
     0.525
hjc
Resolvase, Holliday junction-type, archaeal; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family.
  
   
 0.515
CL1_1740
Hypothetical protein; COG1326.
  
     0.504
nusA
Transcription elongation factor NusA-like protein; Participates in transcription termination. Belongs to the NusA family.
 
     0.501
CL1_0230
Ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
 
   
 0.472
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.