Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0582Hypothetical protein; COG0639. (253 aa)    
Predicted Functional Partners:
CL1_1720
Putative Serine/threonine protein phosphatase; COG0631.
   
 
 0.719
CL1_1602
GTPase; COG1100.
  
 0.604
CL1_1071
DNA/RNA helicase, superfamily II; COG0553.
 
 
 0.593
CL1_1722
Hypothetical protein containing WD40 repeat; COG2319.
  
 0.551
CL1_1570
Hypothetical protein; COG1236.
   
 0.545
CL1_1506
GTP-binding protein 3; COG1100.
   
 0.540
eif2a
Translation initiation factor IF-2 subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.
   
 
 0.498
CL1_1728
Hypothetical protein; COG2319.
   
 0.478
CL1_1870
Aromatic amino acid permease; COG0814.
    
 
 0.439
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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