Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
rpl1850S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (201 aa)    
Predicted Functional Partners:
rpl35ae
50S ribosomal protein L35Ae; COG2451; Belongs to the eukaryotic ribosomal protein eL33 family.
   
 0.999
rpl37ae
50S ribosomal protein L37Ae; Binds to the 23S rRNA.
  
 
 0.999
rpl21e
50S ribosomal protein L21e; COG2139; Belongs to the eukaryotic ribosomal protein eL21 family.
  
 0.999
rpl10
Acidic ribosomal protein P0/50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
 
 0.999
rpl30e
50S ribosomal protein L30e; COG1911; Belongs to the eukaryotic ribosomal protein eL30 family.
  
 0.999
rpl44e
50S ribosomal protein L44e; Binds to the 23S rRNA.
   
 0.999
rpl15e
50S ribosomal protein L15e; COG1632; Belongs to the eukaryotic ribosomal protein eL15 family.
  
 0.999
rpl40e
50S ribosomal protein L40e; COG1552; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.999
rpl13
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 0.999
rpl14e
50S ribosomal protein L14e; COG2163; Belongs to the eukaryotic ribosomal protein eL14 family.
 
 0.999
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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