Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
rpl2250S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (156 aa)    
Predicted Functional Partners:
rpl35ae
50S ribosomal protein L35Ae; COG2451; Belongs to the eukaryotic ribosomal protein eL33 family.
  
 0.999
rpl21e
50S ribosomal protein L21e; COG2139; Belongs to the eukaryotic ribosomal protein eL21 family.
   
 0.999
rpl44e
50S ribosomal protein L44e; Binds to the 23S rRNA.
   
 0.999
rpl14e
50S ribosomal protein L14e; COG2163; Belongs to the eukaryotic ribosomal protein eL14 family.
  
 0.999
rpl34e
Ribosomal protein L34Ae; COG2174; Belongs to the eukaryotic ribosomal protein eL34 family.
  
 0.999
rpl15
50S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
 
 0.999
rpl30
50S ribosomal protein L30; COG1841.
  
 0.999
rps5
30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
  
 
 0.999
rpl18
50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
  
 0.999
rpl19e
50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
  
 0.999
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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