Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0645Hypothetical protein. (101 aa)    
Predicted Functional Partners:
CL1_0646
Hypothetical protein containing metal dependent hydrolase domain; COG1831.
       0.912
CL1_0641
Sulfhydrogenase II, beta chain; COG1145.
       0.863
CL1_0642
Sulfhydrogenase II, gamma chain; COG0543.
       0.863
CL1_0643
Sulfhydrogenase II, delta chain; COG1941.
       0.863
tuf
Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
      
 0.819
CL1_0644
Sulfhydrogenase II, alpha chain; COG3259.
       0.700
CL1_0640
NADH-quinone oxidoreductase subunit E; COG1905.
       0.610
CL1_0638
Glutamate synthase beta chain-related oxidoreductase containing 2Fe-2S and 4Fe-4S clusters; COG0493.
       0.559
CL1_0639
NADH-quinone oxidoreductase subunit F; COG1894.
       0.490
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.