Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CL1_0646Hypothetical protein containing metal dependent hydrolase domain; COG1831. (281 aa)    
Predicted Functional Partners:
CL1_0645
Hypothetical protein.
       0.912
CL1_0641
Sulfhydrogenase II, beta chain; COG1145.
       0.860
CL1_0642
Sulfhydrogenase II, gamma chain; COG0543.
       0.860
CL1_0643
Sulfhydrogenase II, delta chain; COG1941.
       0.860
rpl40e
50S ribosomal protein L40e; COG1552; Belongs to the eukaryotic ribosomal protein eL40 family.
 
     0.743
CL1_0644
Sulfhydrogenase II, alpha chain; COG3259.
       0.679
CL1_1211
Hypothetical protein; COG1549.
  
     0.672
CL1_0014
Hypothetical protein containing SAM domain 1; COG1244.
  
     0.658
CL1_1362
Putative transcriptional regulator; COG1709.
  
     0.643
CL1_1179
Hypothetical protein; COG1772.
  
     0.642
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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