STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0654methylmalonyl-CoA decarboxylase subunit alpha; COG4799. (522 aa)    
Predicted Functional Partners:
CL1_1807
Biotin-protein ligase; COG0340.
 
 
 0.999
CL1_0656
Putative methylmalonyl-CoA decarboxylase subunit gamma; COG0511.
 
  
 0.945
CL1_0657
methylmalonyl-CoA decarboxylase subunit beta; COG1883.
  
  
 0.830
CL1_0655
methylmalonyl-CoA decarboxylase subunit delta; COG3630.
     
 0.827
CL1_1404
acetyl-CoA acetyltransferase; COG0183.
  
 
 0.714
CL1_0652
Cell division control protein, MCM family; COG1241.
       0.678
CL1_0658
Hypothetical protein; COG0517.
  
  
 0.663
CL1_1609
methylmalonyl-CoA mutase, C-terminal domain protein; COG2185.
  
  
 0.643
CL1_1571
methylmalonyl-CoA mutase, alpha chain; COG1884.
  
  
 0.640
eif2b
Translation initiation factor IF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
       0.597
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.