STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0658Hypothetical protein; COG0517. (281 aa)    
Predicted Functional Partners:
CL1_0659
Homoserine dehydrogenase; COG0460.
  
  
 0.868
CL1_0293
Hypothetical protein; COG0517.
  
    0.844
CL1_0654
methylmalonyl-CoA decarboxylase subunit alpha; COG4799.
  
  
 0.843
CL1_0656
Putative methylmalonyl-CoA decarboxylase subunit gamma; COG0511.
     
 0.843
CL1_0655
methylmalonyl-CoA decarboxylase subunit delta; COG3630.
       0.839
CL1_0657
methylmalonyl-CoA decarboxylase subunit beta; COG1883.
       0.839
eif2b
Translation initiation factor IF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
  
    0.768
CL1_0652
Cell division control protein, MCM family; COG1241.
   
 
 0.731
CL1_0663
Hypothetical protein.
       0.658
CL1_1269
Universal stress protein 2; COG0589.
 
    0.595
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.