STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0659Homoserine dehydrogenase; COG0460. (334 aa)    
Predicted Functional Partners:
CL1_0537
Threonine synthase 1; COG0498.
 
 
 0.917
CL1_0387
Ferredoxin; COG1145.
     
  0.900
CL1_1302
Threonine synthase 2; COG0498.
 
 
 0.895
CL1_1427
Hypothetical protein; COG0440.
  
  
 0.890
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
 
  
 0.850
CL1_0055
Chromosome partitioning protein ParB-like protein; COG1475.
    
 0.849
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.826
CL1_1601
Asparagine synthase; COG0367.
  
  
 0.767
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
 
  
 0.721
CL1_0658
Hypothetical protein; COG0517.
  
  
 0.718
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.