| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CL1_0670 | CL1_1915 | CL1_0670 | CL1_1915 | Putative RNA-associated protein; COG1500. | Hypothetical protein containing KH domain; COG1094. | 0.417 |
| CL1_0670 | csl4 | CL1_0670 | CL1_0309 | Putative RNA-associated protein; COG1500. | Hypothetical protein containing nucleic acid -binding domain; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.406 |
| CL1_0670 | dnaG | CL1_0670 | CL1_0409 | Putative RNA-associated protein; COG1500. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.543 |
| CL1_0670 | rps4 | CL1_0670 | CL1_0595 | Putative RNA-associated protein; COG1500. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.712 |
| CL1_0670 | rrp4 | CL1_0670 | CL1_0669 | Putative RNA-associated protein; COG1500. | Exosome complex RNA-binding protein Rrp4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. | 0.874 |
| CL1_0670 | rrp41 | CL1_0670 | CL1_0668 | Putative RNA-associated protein; COG1500. | Exosome complex exonuclease Rrp41; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. | 0.903 |
| CL1_0670 | rrp42 | CL1_0670 | CL1_0667 | Putative RNA-associated protein; COG1500. | Exosome complex RNA-binding protein Rrp42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.888 |
| CL1_1106 | rrp41 | CL1_1106 | CL1_0668 | HamI-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Exosome complex exonuclease Rrp41; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. | 0.882 |
| CL1_1915 | CL1_0670 | CL1_1915 | CL1_0670 | Hypothetical protein containing KH domain; COG1094. | Putative RNA-associated protein; COG1500. | 0.417 |
| CL1_1915 | csl4 | CL1_1915 | CL1_0309 | Hypothetical protein containing KH domain; COG1094. | Hypothetical protein containing nucleic acid -binding domain; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.941 |
| CL1_1915 | dnaG | CL1_1915 | CL1_0409 | Hypothetical protein containing KH domain; COG1094. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.586 |
| CL1_1915 | nep1 | CL1_1915 | CL1_0260 | Hypothetical protein containing KH domain; COG1094. | Ribosome biogenesis protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.999 |
| CL1_1915 | rps4 | CL1_1915 | CL1_0595 | Hypothetical protein containing KH domain; COG1094. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.999 |
| CL1_1915 | rrp4 | CL1_1915 | CL1_0669 | Hypothetical protein containing KH domain; COG1094. | Exosome complex RNA-binding protein Rrp4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. | 0.924 |
| CL1_1915 | rrp41 | CL1_1915 | CL1_0668 | Hypothetical protein containing KH domain; COG1094. | Exosome complex exonuclease Rrp41; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. | 0.885 |
| CL1_1915 | rrp42 | CL1_1915 | CL1_0667 | Hypothetical protein containing KH domain; COG1094. | Exosome complex RNA-binding protein Rrp42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.907 |
| CL1_1915 | rtcA | CL1_1915 | CL1_0647 | Hypothetical protein containing KH domain; COG1094. | RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. | 0.902 |
| csl4 | CL1_0670 | CL1_0309 | CL1_0670 | Hypothetical protein containing nucleic acid -binding domain; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Putative RNA-associated protein; COG1500. | 0.406 |
| csl4 | CL1_1915 | CL1_0309 | CL1_1915 | Hypothetical protein containing nucleic acid -binding domain; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Hypothetical protein containing KH domain; COG1094. | 0.941 |
| csl4 | dnaG | CL1_0309 | CL1_0409 | Hypothetical protein containing nucleic acid -binding domain; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.738 |