STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0686Putative thioesterase; COG2050. (127 aa)    
Predicted Functional Partners:
CL1_0688
Major facilitator superfamily permease 7; COG0477.
     
 0.703
CL1_0687
Transcription regulator, PadR-like familiy 2; COG1695.
       0.694
CL1_0685
Hypothetical protein; COG2886.
       0.645
CL1_1772
Translation initiation factor IF-2B subunit beta; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
      0.607
CL1_0684
Pyrazinamidase/nicotinamidase-like protein; COG1335.
     
 0.564
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
    0.551
CL1_1404
acetyl-CoA acetyltransferase; COG0183.
  
  
 0.470
CL1_1353
Hypothetical protein; COG2151.
  
  
 0.460
CL1_1998
Glucose-1-dehydrogenase; COG1028.
 
  
 0.413
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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