Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CL1_0692Hypothetical protein; COG1107. (741 aa)    
Predicted Functional Partners:
CL1_0693
Major facilitator superfamily permease 8; COG0477.
 
    0.901
CL1_0691
Hypothetical protein; COG0265.
       0.838
CL1_1691
DEAD/DEAH box helicase; COG1202.
  
    0.717
CL1_1576
Hypothetical protein; COG2117.
  
     0.716
rnp3
Ribonuclease P protein component 3; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
  
     0.690
CL1_1740
Hypothetical protein; COG1326.
  
     0.689
CL1_0689
Hypothetical protein.
       0.658
CL1_0350
Hypothetical protein; COG1885; Belongs to the UPF0212 family.
  
     0.647
CL1_0602
Hypothetical protein; COG1422.
  
     0.627
purO
Putative Inosine monophosphate cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP.
 
     0.592
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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