STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0700Hypothetical protein containing sun-domain; COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (451 aa)    
Predicted Functional Partners:
CL1_1401
C/D box methylation guide ribonucleoprotein complex aNOP56 subunit; COG1498.
   
 
 0.663
CL1_0947
Hypothetical protein containing ribosome biogenesis factor; COG1374.
  
 
 0.641
CL1_1027
Hypothetical protein; COG1161.
  
 
 0.637
CL1_0288
Putative GTP-binding protein; COG1084.
   
 
 0.624
rpl35ae
50S ribosomal protein L35Ae; COG2451; Belongs to the eukaryotic ribosomal protein eL33 family.
  
 
   0.583
rps8e
30S ribosomal protein S8e; COG2007.
  
 
 0.579
rpl10
Acidic ribosomal protein P0/50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 
 0.569
CL1_0230
Ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
   
 
 0.559
rpl30
50S ribosomal protein L30; COG1841.
   
 
 0.556
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 
 0.546
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.