Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_0712Metal ion-dependent transcription regulator, DtxR family; COG1321. (145 aa)    
Predicted Functional Partners:
CL1_1911
ABC type manganese/zinc transporter permease; COG1108.
  
  
 0.579
CL1_0025
Manganese/zinc ABC transporter periplasmic protein; COG0803.
  
  
 0.572
CL1_1912
ABC type manganese/zinc transporter ATPase; COG1121.
  
  
 0.539
CL1_1851
Cadmium-translocating P-type ATPase; COG2217.
     
 0.473
CL1_0154
Metalloprotease containing JAB1/MPN domain; COG1310.
       0.459
CL1_1133
NADH-ubiquinone oxidoreductase subunit 4; COG3260.
    
   0.442
CL1_0106
iron(II) transport system protein A; COG1918.
  
  
 0.408
CL1_0107
iron(II) transport system protein B; COG0370.
  
  
 0.402
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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