Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_0726Hypothetical protein containing PIN domain 15; COG1412. (138 aa)    
Predicted Functional Partners:
CL1_1915
Hypothetical protein containing KH domain; COG1094.
  
 0.969
eif2g
Translation initiation factor IF-2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
 
    0.907
CL1_1401
C/D box methylation guide ribonucleoprotein complex aNOP56 subunit; COG1498.
  
 
 0.877
rps6e
30S ribosomal protein S6e; COG2125; Belongs to the eukaryotic ribosomal protein eS6 family.
 
 0.853
CL1_0727
Putative metal-dependent phosphohydrolase; COG3294.
       0.812
CL1_0728
Hypothetical protein; COG2454.
  
    0.779
CL1_1483
H/ACA RNA-protein complex component Gar1; COG3277.
  
 
 0.765
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 
 0.683
rps15
30S ribosomal protein S15; COG0184.
 
   0.678
truB
H/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
   
 
 0.648
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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