| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CL1_0732 | CL1_0733 | CL1_0732 | CL1_0733 | Hypothetical protein containing fmu domain; COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Hypothetical protein. | 0.849 |
| CL1_0732 | CL1_0734 | CL1_0732 | CL1_0734 | Hypothetical protein containing fmu domain; COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Hypothetical protein; COG2263. | 0.810 |
| CL1_0732 | CL1_0735 | CL1_0732 | CL1_0735 | Hypothetical protein containing fmu domain; COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | 0.760 |
| CL1_0732 | rpl37ae | CL1_0732 | CL1_0228 | Hypothetical protein containing fmu domain; COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 50S ribosomal protein L37Ae; Binds to the 23S rRNA. | 0.447 |
| CL1_0733 | CL1_0732 | CL1_0733 | CL1_0732 | Hypothetical protein. | Hypothetical protein containing fmu domain; COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.849 |
| CL1_0733 | CL1_0734 | CL1_0733 | CL1_0734 | Hypothetical protein. | Hypothetical protein; COG2263. | 0.847 |
| CL1_0733 | CL1_0735 | CL1_0733 | CL1_0735 | Hypothetical protein. | Diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | 0.625 |
| CL1_0734 | CL1_0732 | CL1_0734 | CL1_0732 | Hypothetical protein; COG2263. | Hypothetical protein containing fmu domain; COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.810 |
| CL1_0734 | CL1_0733 | CL1_0734 | CL1_0733 | Hypothetical protein; COG2263. | Hypothetical protein. | 0.847 |
| CL1_0734 | CL1_0735 | CL1_0734 | CL1_0735 | Hypothetical protein; COG2263. | Diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | 0.917 |
| CL1_0735 | CL1_0732 | CL1_0735 | CL1_0732 | Diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein containing fmu domain; COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.760 |
| CL1_0735 | CL1_0733 | CL1_0735 | CL1_0733 | Diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein. | 0.625 |
| CL1_0735 | CL1_0734 | CL1_0735 | CL1_0734 | Diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein; COG2263. | 0.917 |
| CL1_0735 | CL1_0738 | CL1_0735 | CL1_0738 | Diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein; COG0393; Belongs to the UPF0145 family. | 0.735 |
| CL1_0735 | CL1_0739 | CL1_0735 | CL1_0739 | Diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein. | 0.710 |
| CL1_0735 | CL1_0740 | CL1_0735 | CL1_0740 | Diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Puativie transcriptional regulator, PadR family; COG1695. | 0.691 |
| CL1_0735 | CL1_1476 | CL1_0735 | CL1_1476 | Diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein; COG2102. | 0.695 |
| CL1_0735 | dphB | CL1_0735 | CL1_1363 | Diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.924 |
| CL1_0735 | fusA | CL1_0735 | CL1_1929 | Diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 0.978 |
| CL1_0735 | rpl37ae | CL1_0735 | CL1_0228 | Diphthamide synthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | 50S ribosomal protein L37Ae; Binds to the 23S rRNA. | 0.696 |
