STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0744Putative carbon-nitrogen hydrolase; COG0388. (264 aa)    
Predicted Functional Partners:
CL1_0205
4-aminobutyrate aminotransferase 1; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.951
CL1_1122
4-aminobutyrate aminotransferase 2; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.950
mfnA
Tyrosine decarboxylase; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily.
  
 
 0.923
CL1_1361
Hypothetical protein; COG1701.
     
  0.900
CL1_1601
Asparagine synthase; COG0367.
  
  
 0.685
CL1_1355
Nicotinate phosphoribosyltransferase; COG1488.
     
 0.637
nadA
Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
     
 0.584
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
  
  
 0.514
CL1_0542
Glutamate dehydrogenase; COG0334; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
 0.512
CL1_0909
Glutamine synthetase; COG0174; Belongs to the glutamine synthetase family.
  
  
 0.497
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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