Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0763Subtilisin-like serine protease; COG1404. (415 aa)    
Predicted Functional Partners:
CL1_0764
Hypothetical protein containing methylase domain; COG2890.
     
 0.628
CL1_0971
Hypothetical protein containing peptidase S8-domain; COG1404.
  
     0.543
CL1_1898
Amino acid transporter; COG0531.
  
 
 0.440
CL1_0273
Putative glycoside hydrolase/deacetylase; COG0726.
 
   
 0.430
CL1_1387
Intracellular protease 1; COG0693.
  
  
 0.428
CL1_1631
Hypothetical protein; COG1030.
     
 0.404
CL1_0472
Hypothetical protein containing peptidase_M50 domain; COG1994.
     
 0.402
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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