STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0764Hypothetical protein containing methylase domain; COG2890. (196 aa)    
Predicted Functional Partners:
prf1
Putative peptide chain release factor 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
   
 0.844
CL1_0934
V-type ATP synthase subunit K; COG0636.
  
   0.643
CL1_0998
Hypothetical protein containing peptidase M50 domain 2; COG0750.
 
  
 0.586
CL1_1598
Putative translation factor, sua5 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
  
  
 0.582
CL1_0763
Subtilisin-like serine protease; COG1404.
     
 0.497
taw1
tRNA-modifying enzyme; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
       0.496
eif5a
Translation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
  
 0.490
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
       0.473
CL1_2036
Translation-associated GTPase; COG0012.
  
  
 0.466
rsmA
16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
     
 0.462
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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