STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0794Formate dehydrogenase subunit alpha FdhA; COG0243. (670 aa)    
Predicted Functional Partners:
CL1_1147
Hypothetical protein containing ferredoxins domain 3; COG0437.
  
 0.974
CL1_1242
Formylmethanofuran dehydrogenase subunit E; COG2191.
 
 
 0.928
CL1_1148
Formate hydrogen lyase subunit alpha; COG0243.
  
  
 
0.904
CL1_0572
Hypothetical protein; COG0446.
    
 0.859
CL1_1373
Putative NADH oxidase 1; COG0446.
    
 0.842
CL1_1143
Hypothetical protein containing ferredoxins domain 1; COG0437.
 
 
 0.757
CL1_0500
Putative NADH-oxidase 2; COG0446.
    
 0.701
CL1_1149
Coenzyme F420-reducing hydrogenase subunit beta; COG1035.
  
 
 0.616
pdxT
Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
     
 0.590
CL1_0640
NADH-quinone oxidoreductase subunit E; COG1905.
 
  
 0.544
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.