STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0807DNA helicase; COG1112. (660 aa)    
Predicted Functional Partners:
taw3
Hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family.
 
     0.930
CL1_1720
Putative Serine/threonine protein phosphatase; COG0631.
   
 
 0.719
CL1_0804
Hypothetical protein; COG1203.
       0.658
CL1_0805
Hypothetical protein.
       0.548
CL1_0806
Hypothetical protein; COG0864.
       0.548
CL1_1570
Hypothetical protein; COG1236.
   
 0.545
CL1_1506
GTP-binding protein 3; COG1100.
   
 0.540
CL1_1602
GTPase; COG1100.
   
 0.540
CL1_1870
Aromatic amino acid permease; COG0814.
  
 
 
 0.540
CL1_1071
DNA/RNA helicase, superfamily II; COG0553.
   
 0.535
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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