STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CL1_0860Hypothetical protein; COG0647. (262 aa)    
Predicted Functional Partners:
CL1_0118
2-hydroxyacid dehydrogenase-like protein; COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.919
CL1_0354
Putative phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
    
 0.919
gyaR
Glyoxylate reductase; COG1052.
  
 
 0.919
CL1_0861
Hypothetical protein; COG1201.
       0.916
rbcL
Ribulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily.
    
  0.901
CL1_0862
Ribonucleoside-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
       0.779
CL1_0851
Hypothetical protein; COG4743.
       0.622
CL1_0859
Putative oligosaccharyl transferase, STT3 subunit 2; COG1287.
       0.593
CL1_0863
Hypothetical protein containing phosphoribosyltransferase-lilke domain 2; COG2236.
       0.535
egsA
NAD(P)-dependent glycerol-1-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
 
  
 0.500
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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