STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_08652'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (184 aa)    
Predicted Functional Partners:
rtcB
Hypothetical protein; COG1372; Belongs to the RtcB family.
 
   
 0.772
CL1_0862
Ribonucleoside-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
       0.543
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp).
 
   
 0.501
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
       0.477
CL1_0864
Hypothetical protein.
       0.470
CL1_0863
Hypothetical protein containing phosphoribosyltransferase-lilke domain 2; COG2236.
       0.461
CL1_0085
Competence damage-inducible protein A; COG1058; Belongs to the CinA family.
     
 0.458
CL1_1311
2-amino-3-ketobutyrate coenzyme A ligase; COG0156.
  
  
 0.430
CL1_0035
Putative phosphomethylpyrimidine kinase; COG1992.
       0.400
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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