STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0891Phosphopentomutase; COG1109; Belongs to the phosphohexose mutase family. (454 aa)    
Predicted Functional Partners:
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
 
 0.954
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
 
 0.939
CL1_0414
Putative mannose-1-phosphate guanylyltransferase; COG1208.
 
  
 0.923
CL1_0467
Putative phospho-sugar mutase; COG1109.
  
 
 
0.915
rpiA
Ribose-5-phosphate isomerase, type A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.913
CL1_1233
Hypothetical protein containing ribokinase-like domain 2; COG0524; Belongs to the carbohydrate kinase PfkB family.
  
 
 0.912
CL1_0890
Hypothetical protein; COG1255; Belongs to the UPF0146 family.
       0.906
CL1_0109
Putative sugar-phosphate nucleotidyltransferase; COG1208.
 
  
 0.855
CL1_0886
Maltooligosaccharide transport system permease protein 1; COG1175.
     
 0.846
CL1_0887
Maltooligosaccharide transport system permease protein 2; COG3833.
     
 0.825
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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