Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0897Hypothetical protein containing SAM domain 5; COG0500. (247 aa)    
Predicted Functional Partners:
CL1_0896
Hypothetical protein; COG0624.
     
 0.877
CL1_0895
Hypothetical protein.
       0.831
CL1_0893
Hypothetical protein; COG1235.
 
  
 0.795
CL1_0894
Oligopeptide transporter, OPT family; COG1297.
       0.764
CL1_0924
Hypothetical protein; COG0037.
 
 
 0.585
CL1_0104
Putative ATPase 1; COG0037.
 
 
 0.526
CL1_1313
Replication factor C small subunit; COG1372.
  
     0.519
pfkC
ADP-specific phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
  
     0.491
rps5
30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
    
 0.466
CL1_1818
CRISPR-associated Cas6 family protein 2; COG1583.
  
     0.451
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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