STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
CL1_0917Dipeptide/oligopeptide ABC transporter substrate-binding protein; COG3889. (805 aa)    
Predicted Functional Partners:
CL1_0915
Dipeptide/oligopeptide ABC transporter permease 1; COG1173.
 
     0.862
CL1_0916
Dipeptide/oligopeptide ABC transporter permease 2; COG0601.
 
     0.854
CL1_0914
Dipeptide/oligopeptide ABC transporter ATPase 4; COG0444.
 
     0.824
CL1_0910
Putative drug/metabolite transporter 3; COG0697.
 
     0.811
CL1_0913
Dipeptide/oligopeptide ABC transporter ATPase 3; COG4608.
       0.797
CL1_0912
Hypothetical protein.
       0.781
nadE
Putative NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
 
     0.763
pyrK
Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
       0.761
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
       0.757
CL1_0920
Hypothetical protein; COG0535.
 
     0.536
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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