STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
secDPutative preprotein translocase subunit SecD; Involved in protein export. (507 aa)    
Predicted Functional Partners:
secF
Putative preprotein translocase subunit SecF; Involved in protein export.
 
 0.999
CL1_0937
Trk-type pottasium transport system, NAD-binding component; COG0569.
 
    0.846
CL1_0927
alanyl-tRNA synthetase 1; COG2872.
  
    0.671
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
  
 0.645
CL1_0934
V-type ATP synthase subunit K; COG0636.
  
    0.628
CL1_0998
Hypothetical protein containing peptidase M50 domain 2; COG0750.
 
  
 0.626
atpC
V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
     0.622
thrS
threonyl-tRNA synthetase; COG0441; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.605
pheT
phenylalanyl-tRNA synthetase beta subunit; COG0072.
 
 
 
 0.600
eif5a
Translation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
 
 0.595
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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