STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
secFPutative preprotein translocase subunit SecF; Involved in protein export. (304 aa)    
Predicted Functional Partners:
secD
Putative preprotein translocase subunit SecD; Involved in protein export.
 
 0.999
CL1_0937
Trk-type pottasium transport system, NAD-binding component; COG0569.
       0.818
srp54
Signal recognition particle protein SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
  
 0.623
CL1_0936
V-type ATP synthase subunit H.
  
    0.605
atpC
V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
     0.599
CL1_0935
V-type ATP synthase subunit I; COG1269; Belongs to the V-ATPase 116 kDa subunit family.
       0.593
CL1_0934
V-type ATP synthase subunit K; COG0636.
  
    0.591
ftsY
Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
     
 0.556
thrS
threonyl-tRNA synthetase; COG0441; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.532
atpF
V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.528
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.