Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1002Hypothetical protein; COG1472. (205 aa)    
Predicted Functional Partners:
CL1_1001
Hypothetical protein.
       0.845
CL1_1004
Transcription regulator, ArsR family 6; COG1846.
     
 0.715
CL1_1003
Hypothetical protein.
       0.680
CL1_1000
Putative ATPase 3; COG1373.
       0.651
CL1_0999
Putative ATPase 2; COG0037.
  
    0.610
CL1_0032
Hypothetical protein; COG3503.
  
    0.522
CL1_0998
Hypothetical protein containing peptidase M50 domain 2; COG0750.
     
 0.469
CL1_1160
ABC type transporter permease 1; COG0842.
  
  
 0.465
CL1_1677
ABC type multidrug transporter permease; COG0842.
  
  
 0.465
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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