Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1027Hypothetical protein; COG1161. (357 aa)    
Predicted Functional Partners:
CL1_0288
Putative GTP-binding protein; COG1084.
  
 
 0.970
rps8e
30S ribosomal protein S8e; COG2007.
   
 
 0.916
CL1_1026
Hypothetical protein.
       0.916
rpl30
50S ribosomal protein L30; COG1841.
   
 
 0.914
rpl10
Acidic ribosomal protein P0/50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 
 0.888
CL1_0947
Hypothetical protein containing ribosome biogenesis factor; COG1374.
   
 
 0.880
CL1_0230
Ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
   
 
 0.874
rpl18
50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
  
 
 0.871
eif6
Translation initiation factor IF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
  
 
 0.864
rpl24
50S ribosomal protein L24P; Located at the polypeptide exit tunnel on the outside of the subunit.
  
 
 0.859
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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