CL1_1050 protein (Thermococcus cleftensis) - STRING interaction network

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Score

CL1_1050

Hypothetical protein; COG1935. (127 aa)

Predicted Functional Partners:

CL1_1049

0.986

mtnP

0.759

CL1_1048

0.411

mtaD

0.405

Your Current Organism:

Thermococcus cleftensis

NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CL1_1048	CL1_1049	CL1_1048	CL1_1049	Hypothetical protein; COG1012.	Hypothetical protein; COG1938.	0.416
CL1_1048	CL1_1050	CL1_1048	CL1_1050	Hypothetical protein; COG1012.	Hypothetical protein; COG1935.	0.411
CL1_1048	mtnP	CL1_1048	CL1_1047	Hypothetical protein; COG1012.	Purine phosphorylase family 2 related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.	0.582
CL1_1049	CL1_1048	CL1_1049	CL1_1048	Hypothetical protein; COG1938.	Hypothetical protein; COG1012.	0.416
CL1_1049	CL1_1050	CL1_1049	CL1_1050	Hypothetical protein; COG1938.	Hypothetical protein; COG1935.	0.986
CL1_1049	mtaD	CL1_1049	CL1_1045	Hypothetical protein; COG1938.	N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.	0.418
CL1_1049	mtnP	CL1_1049	CL1_1047	Hypothetical protein; COG1938.	Purine phosphorylase family 2 related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.	0.761
CL1_1050	CL1_1048	CL1_1050	CL1_1048	Hypothetical protein; COG1935.	Hypothetical protein; COG1012.	0.411
CL1_1050	CL1_1049	CL1_1050	CL1_1049	Hypothetical protein; COG1935.	Hypothetical protein; COG1938.	0.986
CL1_1050	mtaD	CL1_1050	CL1_1045	Hypothetical protein; COG1935.	N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.	0.405
CL1_1050	mtnP	CL1_1050	CL1_1047	Hypothetical protein; COG1935.	Purine phosphorylase family 2 related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.	0.759
mtaD	CL1_1049	CL1_1045	CL1_1049	N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.	Hypothetical protein; COG1938.	0.418
mtaD	CL1_1050	CL1_1045	CL1_1050	N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.	Hypothetical protein; COG1935.	0.405
mtaD	mtnP	CL1_1045	CL1_1047	N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.	Purine phosphorylase family 2 related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.	0.980
mtnP	CL1_1048	CL1_1047	CL1_1048	Purine phosphorylase family 2 related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.	Hypothetical protein; COG1012.	0.582
mtnP	CL1_1049	CL1_1047	CL1_1049	Purine phosphorylase family 2 related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.	Hypothetical protein; COG1938.	0.761
mtnP	CL1_1050	CL1_1047	CL1_1050	Purine phosphorylase family 2 related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.	Hypothetical protein; COG1935.	0.759
mtnP	mtaD	CL1_1047	CL1_1045	Purine phosphorylase family 2 related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.	N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.	0.980