Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CL1_1062Hypothetical protein; COG1002. (1279 aa)    
Predicted Functional Partners:
CL1_1071
DNA/RNA helicase, superfamily II; COG0553.
 
     0.884
CL1_0547
Hypothetical protein containing fibronectin-binding protein; COG1293.
  
    0.875
CL1_1063
Hypothetical protein; COG4252.
       0.773
CL1_1065
Hypothetical protein; COG0249.
       0.695
CL1_1064
Hypothetical protein.
       0.693
CL1_0337
Putative DNA/RNA repair helicase; COG1061.
  
  
 0.530
CL1_1061
Hypothetical protein.
       0.481
polC
DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
 
     0.473
CL1_0168
Hypothetical protein containing peptidase M50 domain 1; COG0750.
  
   
 0.449
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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