CL1_1071 protein (Thermococcus cleftensis) - STRING interaction network

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Score

CL1_1071

DNA/RNA helicase, superfamily II; COG0553. (1128 aa)

Predicted Functional Partners:

rpoK

0.951

rpoD

0.949

CL1_0440

0.945

CL1_0223

0.944

CL1_1867

0.934

fen

0.918

pcn

0.915

rpoN

0.914

rpoH

0.891

CL1_1412

0.886

Your Current Organism:

Thermococcus cleftensis

NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CL1_0223	CL1_0440	CL1_0223	CL1_0440	Putative TBP-interacting protein DNA helicase Tip49-like protein; COG1224.	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.403
CL1_0223	CL1_1071	CL1_0223	CL1_1071	Putative TBP-interacting protein DNA helicase Tip49-like protein; COG1224.	DNA/RNA helicase, superfamily II; COG0553.	0.944
CL1_0223	CL1_1412	CL1_0223	CL1_1412	Putative TBP-interacting protein DNA helicase Tip49-like protein; COG1224.	Putative histone deacetylase; COG0123.	0.600
CL1_0223	fen	CL1_0223	CL1_1585	Putative TBP-interacting protein DNA helicase Tip49-like protein; COG1224.	Flap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...]	0.403
CL1_0223	rpoH	CL1_0223	CL1_0439	Putative TBP-interacting protein DNA helicase Tip49-like protein; COG1224.	DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.	0.806
CL1_0440	CL1_0223	CL1_0440	CL1_0223	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Putative TBP-interacting protein DNA helicase Tip49-like protein; COG1224.	0.403
CL1_0440	CL1_1071	CL1_0440	CL1_1071	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA/RNA helicase, superfamily II; COG0553.	0.945
CL1_0440	CL1_1867	CL1_0440	CL1_1867	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription elongation factor S (TFS_arch); COG1594; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.973
CL1_0440	fen	CL1_0440	CL1_1585	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Flap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...]	0.678
CL1_0440	pcn	CL1_0440	CL1_1865	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA polymerase sliding clamp protein; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.	0.603
CL1_0440	rpoD	CL1_0440	CL1_0593	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.	0.999
CL1_0440	rpoH	CL1_0440	CL1_0439	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.	0.999
CL1_0440	rpoK	CL1_0440	CL1_0588	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.	0.997
CL1_0440	rpoN	CL1_0440	CL1_0589	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.	0.990
CL1_1071	CL1_0223	CL1_1071	CL1_0223	DNA/RNA helicase, superfamily II; COG0553.	Putative TBP-interacting protein DNA helicase Tip49-like protein; COG1224.	0.944
CL1_1071	CL1_0440	CL1_1071	CL1_0440	DNA/RNA helicase, superfamily II; COG0553.	DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.945
CL1_1071	CL1_1412	CL1_1071	CL1_1412	DNA/RNA helicase, superfamily II; COG0553.	Putative histone deacetylase; COG0123.	0.886
CL1_1071	CL1_1867	CL1_1071	CL1_1867	DNA/RNA helicase, superfamily II; COG0553.	Transcription elongation factor S (TFS_arch); COG1594; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.934
CL1_1071	fen	CL1_1071	CL1_1585	DNA/RNA helicase, superfamily II; COG0553.	Flap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...]	0.918
CL1_1071	pcn	CL1_1071	CL1_1865	DNA/RNA helicase, superfamily II; COG0553.	DNA polymerase sliding clamp protein; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.	0.915