STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1100Hypothetical protein; COG0476. (232 aa)    
Predicted Functional Partners:
CL1_1099
Molybdopterin converting factor, subunit 1; COG1977.
 
 0.993
CL1_1102
Molybdopterin converting factor subunit 2; COG0314.
 0.987
CL1_1901
Molybdopterin converting factor, subunit 1; COG1977.
  
 0.964
rpl40e
50S ribosomal protein L40e; COG1552; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.941
CL1_0449
Putative sulfur carrier protein ThiS; COG2104.
  
 
 0.889
thiC
Putative thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
  
 0.808
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
   
 
 0.783
CL1_0035
Putative phosphomethylpyrimidine kinase; COG1992.
 
  
 0.778
CL1_2011
Molybdenum cofactor biosynthesis protein MoeB; COG0521.
 
   
 0.707
moaA
Molybdenum cofactor biosynthesis protein A2; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
  
 0.688
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.