Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
CL1_1123Thioredoxin reductase; COG0492. (330 aa)    
Predicted Functional Partners:
CL1_1996
Putative pyridine nucleotide-disulfide oxidoreductase; COG0492.
  
  
 
0.921
CL1_0492
Putative cysteine desulfurase; COG0520.
  
 
  0.908
CL1_1125
Putative ATPase (AAA+ superfamily) 7.
     
 0.854
CL1_1124
Hypothetical protein; COG1988.
       0.850
CL1_0385
Glutaredoxin-like protein 2; COG0526.
 
 
 0.821
CL1_1122
4-aminobutyrate aminotransferase 2; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.813
CL1_1126
RNA-binding protein containing THUMP domain; COG1818.
       0.796
CL1_1862
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.734
CL1_0211
Glutaredoxin/thioredoxin-like protein; COG0526.
  
 
 0.688
CL1_1121
Hypothetical protein; COG4720.
  
    0.671
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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