STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1124Hypothetical protein; COG1988. (176 aa)    
Predicted Functional Partners:
CL1_1125
Putative ATPase (AAA+ superfamily) 7.
     
 0.916
CL1_1123
Thioredoxin reductase; COG0492.
       0.850
CL1_1126
RNA-binding protein containing THUMP domain; COG1818.
       0.842
CL1_1122
4-aminobutyrate aminotransferase 2; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.751
CL1_0365
Bifunctional D-arabino 3-hexulose-6-phosphate formaldehyde lyase/phosphohexuloisomerase; COG0794.
     
 0.441
CL1_1127
Rubrerythrin-like protein 2; COG1633.
       0.405
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: low (28%) [HD]