STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1155Putative signal peptidase I; COG0681. (188 aa)    
Predicted Functional Partners:
CL1_1180
Signal peptidase I; COG0681.
  
  
  0.934
CL1_0754
Signal peptidase I, S26B family; COG0681.
  
  
  0.922
CL1_1153
MiaB-like tRNA modifying enzyme, archaeal-type; COG0621.
 
    0.565
CL1_0824
Hypothetical protein containing Trimeric LpxA-like domain; COG0110.
  
  
 0.488
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
  
 0.488
secD
Putative preprotein translocase subunit SecD; Involved in protein export.
  
  
 0.485
CL1_1154
Hypothetical protein; COG0804.
       0.417
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.